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Table 2 Comparison of performance of three methods for diagnosis of CL from suspected lesions against consensus standard (gold standard, positive = 52, negative = 91)

From: Evaluation of microcapillary culture method for the isolation of Leishmania aethiopica parasites from patients with cutaneous lesions in Ethiopia

Diagnostic method No. of positive No. of negative Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Direct microscopy 37 106 71.2 97.8 94.6 84.0
MCM 48 95 92.3+† 97.8 96.0 95.7
TCM 36 107 69.2 98.9 97.3 84.9
  1. +P = 0.003 versus TCM by z test, P = 0.0018 versus direct microscopy by z test